Diabetes Mellitus: An Introduction}

Submitted by: My Insupen

Diabetes is a common term for several metabolic disorders in which blood glucose level increases due to the inadequate production of insulin in the Beta-cells of the pancreas. This leads to a condition where the body no longer produces insulin or uses the insulin produced in an ineffective manner. Insulin is a hormone needed to break down sugar and starch into simpler compounds. The cause of diabetes is attributed to both genetics and environmental factors such as obesity & lack of exercise that appear to play important roles.

Often referred to as diabetes mellitus, diabetes refers to a group of metabolic diseases in which the person has high blood glucose (blood sugar), either because insulin production is inadequate, or because the body’s cells do not respond properly to insulin, or both. Patients with high blood sugar will typically experience polyuria (frequent urination) which results in them experiencing extreme thirst (polydipsia) and hunger (polyphagia).

Diabetes (diabetes mellitus) is classified as a metabolic disorder. Metabolism refers to the way our body uses digested food for energy and growth. Most of what we eat is broken down into glucose. Glucose is a form of sugar present in the body and is the principal source of fuel for cellular activities.

Insulin is a hormone that is produced by the pancreas. After eating, the pancreas automatically releases an adequate quantity of insulin to move the glucose present in our blood into the cells. As soon as glucose enters the cells, blood-glucose level drops.

A person with diabetes has a condition in which the quantity of glucose in the blood is too elevated leading to hyperglycemia. This is because the body does not produce enough insulin, produces no insulin, or has cells that do not respond properly to the insulin produced by the pancreas. This excess blood glucose eventually passes out of the body in urine. Therefore, even with a sufficient amount of glucose, cells may not have access to it for their essential energy and growth requirements.

Why is it called diabetes mellitus?

Diabetes comes from Greek, and it means a “siphon”. Aretus the Cappadocian, a Greek physician during the second century A.D., named the condition diabainein. He described patients who were passing too much water (polyuria) – like a siphon. The word became “diabetes” from the English adoption of the Medieval Latin word diabetes.

In 1675, Thomas Willis added mellitus to the term, although it is commonly referred to simply as diabetes. Mel in Latin means “honey”; the urine and blood of people with diabetes has excess glucose, and glucose is sweet like honey. Diabetes mellitus literally means “siphoning off sweet water”.

In ancient China people observed that ants would be attracted to some people’s urine, because it was sweet. Thus, the term “Sweet Urine Disease” was coined.

Types of diabetes

There are three main types of diabetes:

Type 1 diabetes is an auto-immune disease where the body’s immune system attacks the insulin producing cells of the pancreas. People with type 1 diabetes cannot produce insulin and require lifelong insulin injections for survival. This condition mostly occurs in children and young adults. Type 1 diabetes is sometimes referred to as juvenile onset diabetes or insulin dependent diabetes.

Type 2 diabetes is associated with hereditary factors and lifestyle risk factors including poor diet, insufficient physical activity and obesity. People with type 2 diabetes may be able to manage their condition through lifestyle changes; however, diabetes medications or insulin injections may also be required to control blood sugar levels.

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Gestational diabetes occurs during pregnancy. This condition usually disappears once the baby is born. However, a history of gestational diabetes increases a woman’s risk of developing type 2 diabetes later in life. The condition may be managed through adopting healthy dietary and exercise habits, although diabetes medication, including insulin, may also be required to manage blood sugar levels.

Symptoms of diabetes:

Frequent urination

Extreme thirst and/or hunge

Weight loss

Fatigue

Numbness

Sores that are slow to heal, and

Increased infections

People with type 2 Diabetes may have no symptoms for nearly 5-7 years after high glucose levels develop. Even when there are no symptoms, they may experience vague symptoms like tiredness, muscle pain, headache, anxiety, etc.

Poor control of diabetes can lead to an increased risk of:

Heart disease

High blood pressure

Stroke

Nerve disease

Kidney and bladder failure

Gum disease

Blindness

Foot and leg infections

Sexual Dysfunction

Complications in pregnancy

Uncontrolled diabetes can lead to biochemical imbalances that can cause acute life-threatening events, such as diabetic ketoacidosis and hyperosmolar (nonketotic) coma.

INSUPen- Helping You Manage Diabetes With EASE

Gone are the days when diabetes took the zest out of life. Advanced research has resulted in better therapies and improved the quality of life for many diabetics globally. After years of rigorous research, Biocon along with Germanys leading Designer, Haselmeier GmbH has come out with a way to change Diabetes to Diabetease by launching the INSUPen.

With state-of-the-art technology and features that complement todays lifestyle, INSUPen helps manage Diabetes in an Efficient, Accurate, Safe and Economical way.

Why INSUPen is the most sought after Insulin Pen?

A breakthrough insulin delivery device with three unique firsts:

First German technology insulin pen offering the best user-friendly features

First to offer a choice of 3 colours

First to offer complimentary needles with every Refil

Innovative packaging:

Comprehensive packaging ensures comfort all the way

Basal Analogue Refil in packs of threes and ones

Insulin Refil in packs of fives and ones

An affordable innovation:

Easy on pockets in the long run

About the Author: 1. My INSUPen Homepage:

myinsupen.com/

2. INSUPen for Doctors and Healthcare Professionals:

myinsupen.com/insupen-doctors/

3. INSUPen for patients and caregivers:

myinsupen.com/insupen-patients/

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